Peer-reviewed / Open Access

Original Research Article

(NOTE: If you are reading a printout of these manuscript submission guidelines, please note that all website links indicated below can be found at

Original Research Articles report results of research in clinical medicine, pharmaceutical development, epidemiology, health strategies, international health cooperation, or training in the health professions. The text is limited to 5000 words (6000 words in Spanish), plus 5 tables/figures/images and no more than 50 references. All submissions to this section are subject to double-blind peer review.


Maximum length 5000 words (6000 in Spanish). Submit in MSWord, single-spaced in 12-point Times New Roman. Do not use any preset or automatic formatting or style features. All macros must be disabled.

Title Page

  • Title
  • Names, degrees and institutional affiliations of all authors. Lead author’s name should be listed first. (See Definitions of Author & Contributor).
  • Contact information for the corresponding author (email, mailing address, and work/home/cellphone numbers).

The abstract must include: Introduction (context and background of the topic and the study); Objective (purpose of the study); Methods (materials and methods used, including selection of subjects; study design; description of observation methods, measurements and other activities; and data collection/processing, statistical and other analyses); Results (main findings), and Conclusions (new discoveries, most relevant findings and recommendations)..Abstracts should accurately reflect the content of the manuscript, and are limited to 400 words.

Provide 3–10 keywords.  See Medical Subject Headings (MeSH) list.

Body Text
Follow the “IMRAD” (Introduction, Methods, Results and Discussion) heading structure specified in the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (URM). Include Conclusion(s) at the end of the Discussion section.

For some manuscripts, such as those related to medical education, a similar and more appropriate structure may be adopted (such as Introduction, Intervention, Results, Discussion, and Conclusion).

The following format guide is summarized and adapted from the Uniform Requirements for Manuscripts Submitted to Biomedical Journals, where more extensive explanations and precisions are available for authors:

  • Introduction: indicate the context or background for the study in Cuba or the country/region where it was carried out, as well as global significance of the problem or issue addressed. State the specific purpose or research objective of, or hypothesis tested by, the study or observation.
  • Methods: describe the type of study, how and why it was carried out with a particular design or protocol. Include: participant selection (universe, criteria, ethical aspects); variables considered; equipment used (name, brand, country); any modifications made to heretofore recognized methods for similar studies; data collection and processing (include software programs used); methods of statistical analysis; and any other details that would permit readers to duplicate methodology.
  • Results: Summarize results in logical sequence of variables considered, emphasizing most relevant findings first. Do not repeat in the text all the data provided in graphics. Present results with appropriate indicators, and include confidence intervals where necessary.
  • Discussion: Limit discussion to the results obtained, highlighting new and important conclusions derived from these. Do not repeat information from the Introduction or Results section, but rather explore possible mechanisms or explanations for findings, compare with other relevant studies. Limitations of the current study should be clearly stated.
  • Conclusions: Link to the study objectives, and describe implications of findings for future research and practice. Avoid generalizations not entirely supported by the current research; or references to economic benefits and costs if the article has not included economic data or analysis.

Mention individuals who contributed to the manuscript, but whose contribution does not justify authorship. Financial and material support should also be acknowledged. (See Definitions of Author & Contributor).


Include no more than 50 references. These should include the most current relevant literature and wherever possible refer to original research rather than review articles. References should be numbered consecutively in the body of the text and appear within brackets, for example: [2].The list of references cited should appear at the end of the text, after the Conclusions.

MEDICC Review follows a standard citation style. See Citing Medicine, The NLM Style Guide for Authors, Editors, and Publishers. For abbreviations of journal titles cited, see Index Medicus


Submit a maximum of 5 tables and/or figures or images.

All files must be submitted digitally. Files should be named for easy reference (example: Pérez Fig.1.jpg).

Images may be in grayscale or color (ideally CMYK, though RGB files are acceptable). Do not send GIF images or files in 256-color format.

Number consecutively in order of appearance in the text. Include title and data source. Submit in a separate digital file.  

Number consecutively. Include title and data source. Submit as separate files in the format in which they were originally created. MEDICC Review accepts: 1) original files in Illustrator, Corel Draw, MS Word, Freehand, Excel or PowerPoint; 2) as postscript files (*.ps); or as 3) bitmap files.

For bitmap files: send in Tiff (*.tif), Adobe Photoschop (*.psd), JPEG (*.jpg), PDF (*.pdf) or Photoshop EPS (*.eps), with a minimum resolution of 300 dpi (dots per inch), uncompressed.

Images & Photographs
Image resolution must be at least 300dpi (dots per inch). Accepted formats include: TIFF (*.tif), Adobe Photoshop (*.psd), JPEG (*.jpg), PDF (*.pdf) or Photoshop EPS (*.eps).

Do not imbed images or photographs in Word documents, since resolution will not be adequate. Likewise, do not send images or illustrations downloaded from the Internet.

Include appropriate credits and captions.

Authors must guarantee in writing that they have the right to publish photos and images subject to copyright and that they alone bear full responsibility in case of infringement, exonerating MEDICC Review of all responsibility.

Questions?  Contact our design department at:

Units of Measurement
Use those established by the International System of Units (ISU); measurements should be in metric units; temperatures in degrees Celsius. NOTE: In decimal units, use periods, not commas, as follows:  0.15 or 3.1%, etc.

Author Agreement & Conflict of Interest
Sign and submit with your manuscript the MEDICC Review Author Agreement, which includes the Conflict of Interest Declaration.

Read MEDICC Review’s Conflict of Interest Policy carefully before submitting your Author Agreement form. Full disclosure of any relationships that could be perceived as potential conflicts of interest must be indicated. Conflict of interest can be financial, personal or professional. The editors will publish all declared potential conflicts of interest.

Submission Checklist

□ Title Page with correct contact information

□ Manuscript text in MSWord 12-point Times New Roman (maximum length 5,000 words or 6000 in Spanish plus references)

□ Tables in separate file

□ Figures in original format and separate files

□ Images in separate files

MEDICC Review Author Agreement, including Conflict of Interest Declaration (signed by all authors and scanned for submission)

All manuscripts must be submitted electronically to:

Useful References

Citing Medicine, The NLM Style Guide for Authors, Editors, and Publishers

Uniform Requirements for Manuscripts Submitted to Biomedical Journals

MeSH (Keyword Headings)

MEDICC Review Author Agreement

MEDICC Review Editorial Ethics

Author’s Copies

Lead authors will receive 5 complimentary copies of the issue of MEDICC Review in which their work appears. Each co-author will receive one copy.